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Helicobacter Pylori bacterium, which usually causes ulcers
and stomach cancer may protect children from developing asthma, a study
published online in the Journal of Infectious Diseases suggests.
Lead authors Yu Chen, assistant professor of epidemiology at
New York University School of Medicine and Martin J. Blaser, MD professor of
microbiology at NYU Langone Medical
Center along with their colleagues analyzed
data on 7,412 US children
from the National Health and Nutrition Survey conducted from 1999 to 2000 by
the National Center for Health Statistics.
The study found that children ages 3 to 13 who tested
positive for H. pylori were 59 percent less likely to have asthma compared to
children who did not have the bacterium.
The study showed that 5.4 percent of children born in the
1990s tested positive for H. pylori. Also, the presence of the bacterium was
linked to less wheezing and dermatitis, eczema or rash.
“The disappearance of Helicobacter ... is consistent with the decline of
both ulcer disease and stomach cancer. It is also consistent with the rise of
asthma and esophageal diseases like GERD (gastric reflux disease) and adenocarcinoma
(cancer) of the esophagus,” Blaser said.
The researchers support the “hygiene hypothesis” according to which humans
are more prone to allergic disorders because of a lifestyle that may be too “clean.”
When the bacterium is present, the stomach is lined with immune cells called
regulatory T cells. These cells help regulate body’s response to invaders. Without
the cells, a child may be more sensitive to allergens, therefore to asthma.
Also, previous studies have shown that antibiotics used to treat H. pylori
early in childhood increases risk of asthma and there is a great body of
evidence that parents and doctors are using antibiotics like water. This
practice needs to be stopped because children’s immune system will no longer
know how to fight allergens.
Asthma is a chronic disease that causes the airways in the lungs to swell
and become inflamed. Although there is no cure, medication can help control the
disease and relieve pressure in the airways during an attack.
According to the Centers for Disease Control and Prevention, about 20
million Americans have asthma, including 9 million children. The number of affected
children has more than doubled since the 1980s, the same figures show.
Image Credit: www.hpylori.com
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