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An extraordinary report was made public by a group of
scientists from Japan. It is for the first time in human history that the
tissue of a 16 year-old frozen mouse was successfully used in a cloning
process.
The tissue was used to produce four healthy mice, spawning
many theories about the countless possibilities brought by this bio-tech
breakthrough. A similar scenario was used for the Jurassic Park movie, with
prehistoric animals brought back to life, but at the time such a procedure was
considered unrealistic. Now, many believe that it won’t be long until
prehistoric mammals located in the arctic tundra will provide all the needed
elements to bring back some of the animals we’ve lost during Earth’s evolution.
The study was presented in the journal Proceedings of the
National Academy of Sciences and was conducted by Sayaka Wakayama of the Center
for Developmental Biology in Kobe.
“It’s not the first time that dead animals have been
resurrected,” said George E. Seidel Jr. of Colorado State University in Fort
Collins, editor of the study. “But previously they were stored much colder than
these temperatures and they were generally treated in a special way.” The focus
will now be turned on the possibility of bringing back animals such as the
woolly mammoth, a huge creature that weighed as much as 6 tons, which
originated in Eurasia more than 250,000 years ago and disappeared by the end of
the Pleistocene era about 10,000 B.C.
"It would be very difficult, but our work suggests that
it is no longer science fiction," team leader Teruhiko Wakayama of the
RIKEN Center for Developmental Biology in Kobe, Japan, said during an interview
with New Scientist magazine.
The news immediately started many debates, as there are several
scientists who believe that such experiments can only be taken so far, considering
it impossible to clone extinct species. They say that there are no live cells
available on the body and that whatever piece of genetic material might be
found is very likely to be degraded and unusable. Still, the same nuclear
transfer techniques could be used on extinct species. The study notes that
"techniques could be used to 'resurrect' animals or maintain valuable
genomic stocks from tissues frozen for prolonged periods without any cryopreservation."
Mr. Seidel explained that an attempt to reproduce a woolly
mammoth is unlikely to happen over the next decade, as there are many aspects
that need to be considered: the cells are expected to die once they are thawed
out and also, at this point there are no live eggs – with the only possibility
being to use an elephant egg to host the woolly mammoth clone. “It’s a long
shot, but it’s evidence along the lines that that might be possible,” Seidel concluded
during a telephone interview.
It is indeed a huge break-through which is expected to also lead
to many others as the possibility of resurrecting some of the lost species
represented up until recently only a distant dream for many scientists.
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