Study Reveals Higher Risk of Breast Cancer In Ethnic Groups
By Dee Chisamera
14:50, December 27th 2007
89 votes
Vote this story
Study Reveals Higher Risk of Breast Cancer In Ethnic Groups

Minority women have a 65 percent chance of getting breast cancer, says a recent study conducted by the Northern California Cancer Center and Stanford University. Responsible for this alarming percentage is the BRCA1 gene, which appears to present abnormal mutations in Ashkenazi Jew women, as well as in Hispanic and African-American women, according to latest studies.

The new cancer research showed that although everyone carries the BRCA1 gene, it is not harmful in any way. On the contrary, it is responsible for making a protein that helps cells repair DNA. The problems appear though when the gene suffers a mutation, which will consequently increase the chance to produce cancer.

According to these studies, focused on multiracial subjects, 8.3 percent of the Ashkenazi Jew females with breast cancer have a mutated BRCA1 gene, while the prevalence of the mutation in other minorities, although not as big, still raises concerns: 3.5 percent for Hispanic women, 2.2 percent in non-Hispanic white women, 1.3 percent among African-American and 0.5 percent of Asian-Americans.

The report published in the Journal of the American Medial Association states that “pathogenic mutations in the tumor suppressor gene BRCA1 confer high risks of breast and ovarian cancer […] Although mutations in BRCA1 are rare, they are more frequently present in individuals with multiple relatives having breast or ovarian cancer, early-onset breast cancer, or of Ashkenazi Jewish ancestry.”

The study was conducted on a total of 3181 patients diagnosed with breast cancer between 1995 and 2003, which have been tested for alterations of the BRCA1 gene during that period. The Hispanic patients included third-generation U.S. born Hispanics (95), patients with origins in Mexico (200), Central America (49), South America (28), the Carribbean (14) or Spain (4).

The Asian-American patients originated from China (200), Filipinas (150), Japan (66), Vietnam (10), Koreea (3) and other parts of Asia, while 331 of the African-American ones were born in the U.S. to U.S.-born parents, 1 in Europe with U.S.-born parents, 4 born in Africa, 2 in Jamaica and 3 from West Indies.

The conclusion of the study is that, no matter the ethnical background, women are exposed to breast and ovarian cancers during their life. Despite the fact that the prevalence of the mutated gene among minority females increases their likelihood of being exposed to breast cancer, this does not exclude the rest of the women, who should do periodical checkups as well. After all, it’s better to prevent than to treat.



© 2007 - 2008 - eFluxMedia
dotclear

Other News in

Genetic Code Of Malaria Parasite Deciphered

Genetic Code Of Malaria Parasite Deciphered

About 40 researchers sequenced the genetic code of Plasmodium vivax, one of four malaria parasites responsible for nearly 40% of the approximate half a billion annual malaria infections that occur...

Research Institutions Collaborate On Genomic Research Project

Jim Doyle announced Friday that Wisconsin’s four academic research institutions will join forces on an initiative focused on making the state a leader in individualized medicine, a science that...

FDA Supports New Limit On Cold And Cough Medicines

FDA Supports New Limit On Cold And Cough Medicines

The Food and Drug Administration told healthcare providers and customers that it agrees with the decision the drug industry took regarding the warning labels for over-the-counter cough and cold...

QVC's Shoe Sales to Help Breast Cancer Research

QVC's Shoe Sales to Help Breast Cancer Research

With October being the Breast Cancer Awareness Month, many are trying to find ways to help raise money for further research into prevention and treatment methods for the deadly disease. In...

Advocacy Group Sues Oklahoma's Law Against Abortion

An Oklahoma law that prohibits a woman from getting an abortion before she undergoes an ultrasound and the doctors describes what her fetus looks like is being sued by the Center for Reproductive...

dotclear
Latest videos in Health
The White House Turns Pink
Teens 'chat' With Scientists...
NY Nursing Home Workers...
Toxic milk alert hits South...
Tainted Milk Scandal Spreads...

dotclear
Health You are here: Health
» Science   » Health   
E-mail To A Friend Print RSS Text size: Decrease font size Increase font size
dotclear
dotclear
dotclear
Most Popular in Health
Update: New Arms For 54-Year-Old German AmputeeUpdate: New Arms For 54-Year-Old German Amputee

» read full story
dotclear

Interested In This Topic?

News Alert will keep you informed. Find out more.
dotclear
Photos Gallery
dotclear
Today's Latest News
A Lot of Sunshine, Beauty and Happiness in "Happy-Go-Lucky”A Lot of Sunshine, Beauty and Happiness in "Happy-Go-Lucky”

» read full story
dotclear