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Lung cancer drug Tarceva jointly developed by OSI
Pharmaceuticals Inc., Genentech Inc. and Roche Holding AG helped slow the
progress of the disease when given immediately after chemotherapy, the companies
announced Friday.
The news comes just a month after a study combining
Genentech cancer drug Avastin and Tarceva showed the treatment failed to
prolong the lives of patients. But the new study called Saturn found Tarceva “significantly
extended” progression-free survival of patients with non-small-cell lung
cancer, one of two main types of the disease.
The study involved 889 patients who were given at least four
cycles chemotherapy and were then treated with either once-daily Tarceva or a placebo
if the disease did not progress during chemotherapy.
“We’re very pleased. With all the progress we’ve made, we
still have a long way to go, but this is a good step. And we definitely need
steps forward,” said Colin Goddard, OSI’s chief executive.
The results of the trial will be later submitted to the US
Food and Drug Administration, where the manufacturers hope to gain approval to
use Tarceva in earlier stages of lung cancer treatment. If Tarceva is approved,
“we would expect to see a pretty decent increase in revenue,” Goddard added.
According to Roche, lung cancer is the most common cancer worldwide
with 1.4 million new cases each year, about 80 percent of lung cancers belong
to a type known as non-small cell lung cancer, the one targeted by Tarceva.
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