Three studies scheduled to be presented this week at the
American College of Rheumatology's annual meeting in San Francisco (Oct. 24-29)
found that rheumatoid arthritis nearly doubles the risk of having a heart
attack. Moreover, people with rheumatoid arthritis who do suffer a heart attack
are prone to have more heart-related complications compared with people without
the condition.
Rheumatoid
arthritis is an autoimmune disease caused by a malfunctioning immune system.
How can you recognize arthritis? Well if you feel pain and stiffness in your
body or have trouble moving around, you might have arthritis. Most kinds of
arthritis cause pain and swelling in your joints. Over time, a swollen joint
becomes severely damaged, but the negative impact on your body doesn’t end here,
as some kinds of arthritis can also cause problems in your organs, such as your
eyes or skin.
The
disease is determined partly by genes and partly by factors such as smoking and
drinking. Previous studies have shown that smoking increases the risk of the
disease.
The Arthritis Foundation estimates that 1.3 million
Americans suffer from rheumatoid arthritis.
The three studies were the work of Dr. Hilal Maradit
Kremers, an epidemiologist at the Mayo Clinic in Rochester,
Minn., Marie Gunnarsson, a doctoral student at
the Institute of Environmental
Medicine at the Karolinska Institute in Stockholm,
Sweden and Dr. Kimberly
Liang, an assistant professor at the University
of Pittsburgh.
Dr. Kremers and colleagues tracked 38 patients with
rheumatoid arthritis who had suffered a heart attack and compared them with
patients without the condition who also had a heart attack.
The study showed that patients with rheumatoid arthritis had
a 45 percent greater risk of developing heart failure after a heart attack compared
with the general population, and a 75 percent greater risk of dying.
“Rheumatoid arthritis patients not only have more heart
attacks and heart failures, but they also have worse prognosis once they have a
cardiovascular event,” said Dr. Kremers.
In the second study, Gunnarsson and colleagues tracked data
on 7,954 newly diagnosed rheumatoid arthritis patients and compared that
information with 38,913 people from the general population in Sweden. The
researchers found that rheumatoid arthritis had almost doubled the risk of a
heart attack and dying from a heart attack over 10 years of follow-up.
The third study found that diastolic dysfunction occurred in
38.9 percent compared to 28.8 percent in the non-rheumatoid arthritis group.
Diastolic dysfunction impairs the ability of the ventricles to fill with blood
and can lead to heart failure.
“We also found that patients in the rheumatoid arthritis
group had higher average pulmonary arterial pressure, which is high blood
pressure in the lungs and the right side of the heart,” Dr. Liang said.
Given the findings, people diagnosed with rheumatoid
arthritis should pay particular attention to cholesterol and blood pressure, known
to increase heart attack risk, Dr. John Hardin, chief science officer at the Arthritis
Foundation, said.