You should care what you eat, especially because the diet
could be your best friend or your worse enemy. Eating healthy, it is not just a
health slogan, but also a way of life.
There are numerous studies that prove that eating fruits and
vegetables may improve your life and health and today at the American
Association for Cancer Research’s Sixth Annual International Conference on
Frontiers in Cancer Prevention the researchers have presented new findings
about the impact of the dietary habits on one of the worse diseases: cancer.
For example, according to the researchers at The Ohio State
University, black raspberries
may protect against esophageal cancer. The scientists said
that in patients with Barrett’s esophagus (BE), a pre-cancerous condition that
usually arises due to gastroesophageal reflux disease, the black raspberries reduced
measures of oxidative stress, decreased DNA damage, inhibited cellular
proliferation rates, and reduced the number of pre-cancerous cells in the esophagus
and colon. BE patients have a 30- to 40-fold increased risk of developing
esophageal adenocarcinoma (EAC), the fastest growing cancer in terms of
incidence in the United
States.
The Ohio State University scientists said that the BE
patients who ate 32 or 45 grams of
freeze-dried black raspberries daily for 26 weeks experienced a statistically
significantly decline in the mean urinary levels of 8-Isoprostane, an indicator
of global oxidative stress and DNA damage - both processes linked to the
development of BE and EAC.
“In addition to gastroesophageal reflux disease, increasing
body mass index or body fatness is strongly associated with EAC development;
whereas, plant-based diets and particularly increased fruit consumption has
been associated with decreased risk for EAC,” said Laura A. Kresty, Ph.D.,
assistant professor of at Ohio State University.
In another study, researchers from Roswell Park Cancer
Institute reported that a diet rich in raw cruciferous vegetables like
broccoli, cabbage and cauliflower could reduce the bladder cancer risk by
approximately 40 percent.
The result was explained by the presence in those vegetables
of the isothiocyanates (ITCs), a known class of cancer prevention agents.
In addition, the researchers said that after taking in
consideration the smoking habits of the surveyed patients, the non-smokers who
ate at least three servings of raw vegetables a month were almost 73 percent
less likely to develop bladder cancer compared to smokers who ate less than
three servings.
A key factor in the research was that it is a survey of raw
cruciferous vegetables. Previous research had surveyed intake of any
cruciferous vegetables – cooked or not – and results proved inconsistent.
Cooking significantly reduces the availability of ITCs for absorption into the
body, according to researchers.
“Cooking can reduce 60 to 90 percent of ITCs,” says Li Tang,
M.D., Ph.D. of Roswell Park Cancer Institute and lead researcher on this study.
“Heating destroys the enzyme that converts the precursor glucosinolates into
ITCs, and also destroys ITCs already formed, which is why you need to eat raw
cruciferous vegetables to receive the food’s maximum benefit.”
In addition, using a rat model of bladder cancer, Yuesheng
Zhang, M.D., Ph.D, professor of oncology at Roswell Park Cancer Institute,
found that freeze-dried aqueous extract of broccoli sprouts significantly, and
dose-dependently, inhibited bladder cancer development. The incidence,
multiplicity, size and progression of bladder cancer were all inhibited by the
extract, while the extract itself caused no observable changes in the bladder.
“The bladder is like a storage bag, and cancers in the
bladder occurs almost entirely along the inner surface, the epithelium, that
faces the urine, presumably because this tissue is assaulted all the time by
noxious materials in the urine,” said senior author Yuesheng Zhang, M.D., Ph.D,
professor of oncology at Roswell Park Cancer Institute. “The ITCs in broccoli
sprout extracts after oral ingestion are selectively delivered to the bladder
epithelium through urine excretion.”
Previous researches proved the beneficial effects of broccoli
in reducing the risk of skin cancer. In a study published in October Dr. Paul
Talalay, from the department of pharmacology and molecular sciences at the
Johns School of Medicine, discovered that
the treatment with broccoli sprout extract might be another
protective measure that alleviates the skin damage caused by UV radiation and,
thereby, decreases long-term risk of
developing cancer.