Last summer’s "Knocked Up" stars Paul Rudd and Jason Segel are almost certainly going to join forces again for DreamWorks’ upcoming comedy "I Love You, Man."

The movie, which is directed and written by John Hamburg, who inked a two-year overall deal with DreamWorks in April, follows a bridegroom’s journey to find a best man. According to the Hollywood Reporter, Rudd is set to play the groom while Segel is tipped to perform the best man’s part.

The shooting for the movie is scheduled to start in March next year.

Donald De Line will be producing alongside Hamburg while Ivan Reitman, Tom Pollock, Bill Johnson and Jeff Clifford are set to executive produce.

The Rudd-Segel duo most recently worked together on Judd Apatow's "Knocked Up," also starring Katherine Heigl, and will appear on screen together in the upcoming "Forgetting Sarah Marshall," which was written by Segel.

Rudd can next be seen on the big screen opposite John C. Reilly in the Apatow-produced "Walk Hard: The Dewey Cox Story" and "Little Big Men," which he co-wrote.

Hamburg’s writing credits include "Meet the Parents," "Meet the Fockers" and "Zoolander."