A new study conducted by the Group Health
Center for Health Studies
has found that there is a direct link between the ability of diagnostic
mammograms to detect breast problems and the radiologist’s experience.
During a seven-year study, the researchers have examined how
well 123 radiologists interpreted nearly 36,000 diagnostic mammograms done to
evaluate breast problems, such as lumps, from 1996 through 2003 at 72 U.S.
facilities, including six from Group Health.
The main criterion of evaluation was the “sensitivity”, the
ability to accurately detect cancer, especially for women with breast symptoms
such as lumps.
According to their findings for different radiologists,
sensitivity ranged from 27 percent to 100 percent; and false-positives, from 0
to 16 percent.
"On average, 21 percent of breast cancers were missed
and 4.3 percent of women underwent a biopsy even though they didn't have breast
cancer," said study leader Diana Miglioretti, PhD, an associate
investigator at Group
Health Center
for Health Studies.
Ideally, this “sensitivity” would be consistently high, with
few false-positives-biopsies performed despite the absence of cancer
The study also revealed the radiologists who read diagnostic
mammograms most accurately (with highest sensitivity, without too many
false-positives) tended to be those who were based at academic medical centers
or spent at least 20 percent of their time on breast imaging.
“We need to reduce the wide variability among radiologists
in how they interpret diagnostic-and screening-mammograms,” said Miglioretti.
“A good way to do that may be to identify the radiologists
who are least accurate at reading mammograms-and to improve their performance
with extra training,” Miglioretti added.
She also urged women with breast concerns, such as lumps, to
try to get evaluated at a center that has at least one breast imaging
specialist: a radiologist who spends a large percentage of the time reading
mammograms and performing breast biopsies.
“Women should get regular screening mammograms,” said
Miglioretti. “Mammography isn’t perfect, but it’s the best way we have to
detect breast cancer early, when it has the greatest chance of being cured.”
On Sunday, in another study, the scientists announced that they
have discovered that women, who inherit a version of the gene BRCA1 that
suffered a mutation, are more inclined to develop breast cancer. This discovery
might help in finding new treatments.
There will be an estimated 178,000 new cases of breast
cancer in the United States
this year, with 40,000 deaths.