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Merck’s HPV vaccine Gardasil was found to be effective in
men as well, this time preventing genital warts, a sexually-transmitted problem
that is embarrassing and uncomfortable though not life-threatening.
Gardasil got the Food and Drug Administration approval back
in 2006. The vaccine is given to teenage girls and young women as protection
against four strains of the human papillomavirus, two of which accounting for
about 70 percent of cervical cancer cases. Last month, Gardasil received FDA
approval for vulvar and vaginal cancers as well. These cancers affect more than
5,000 women annually in the United
States.
The CDC currently recommends Gardasil for 11 and 12-year-old
girls, because nearly none of them has begun their sex lives, and therefore
they haven’t been exposed to the virus. For that reason, Gardasil will offer
them maximum protection.
Now, the Merck study says Gardasil is effective in
preventing genital warts in boys as well. The study involved about 4,000 males
ages 16 to 26 from nearly 20 countries. It showed the vaccine was 90 percent
effective in preventing genital warts, with only 15 cases of persistent
infection in a vaccinated group of males as compared to 101 cases in a group
that was given a fake vaccine.
“This is groundbreaking data. To demonstrate that Gardasil
prevents infection and disease at a very high level in males - that's the other
half of the world,” said Anna Giuliano, professor of medicine and epidemiology
at University of South Florida, who co-authored the study.
The results of the study were presented Thursday at a
medical conference in Europe.
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