The latest study on breast cancer appears to question the efficiency
of an MRI or magnetic resonance imaging given to more newly diagnosed breast
cancer patients before surgery.
To be more specific, the study strongly supports that getting
an MRI appears to delay the start of treatment by three weeks, which may not
affect a woman’s survival, but certainly adds to her anxiety. Also, the study
showed that women having MRIs are more likely to get mastectomies, instead of
breast-conserving lumpectomies, mostly because MRIs can pick up suspicious
spots outside the original lump.
For the study, Dr. Richard Bleicher, a breast cancer surgeon
at Fox Chase
Cancer Center
in Philadelphia
and colleagues analyzed 577 breast cancer patients who had been evaluated by a
radiologist, pathologist and a surgical, radiation and medical oncologist. The
findings were presented Saturday at a meeting of the American Society of
Clinical Oncology in Washington
D.C.
The study found that 130 of the patients had MRIs before
surgery to remove their tumors and 27.7 percent of these had a mastectomy. Of those
not having MRIs, 19.5 percent had a mastectomy. These figures clearly state
that having an MRI almost doubled the chances that a woman would undergo a
mastectomy. One possible explanation for this finding was that the MRI, being
highly sensitive, might have picked up something that looked like cancer but
turned out not to be – a false positive.
The findings add to research presented earlier this year by
Mayo Clinic researchers who found that the mastectomy rate has increased to
levels close to those not seen since 1997.
“MRI may not be as good as we think it is. Those who
received an MRI had a three-week delay in the start of their treatment. In
addition to the treatment delay, we’re concerned that the well-documented
false-positive rate with MRIs may be leading – or misleading – women into
choosing mastectomies,” Dr. Bleicher said.
He further added that “MRIs are valuable and should be done
in certain women at high risk, but they are not appropriate in routine
evaluation of breast cancer.”
However, more research needs to be done in order “to come up
with a general recommendation. It’s not a cut-and-fried issue,” Debbie Saslow,
director of breast and gynecologic cancer at the American Cancer Society, said.
According to the American Cancer Society, breast cancer is
the top cause of cancer death among women worldwide with an estimated 500,000
death annually. In the US
each year, more than 180,000 new breast cancer cases are diagnosed and more
than 40,000 women die because of it.
The study was supported by a U.S. Public Health Service
grant and by an appropriation from the Commonwealth of Pennsylvania.