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About 40 researchers sequenced the genetic code of
Plasmodium vivax, one of four malaria parasites responsible for nearly 40% of
the approximate half a billion annual malaria infections that occur worldwide.
The team of researchers, led by Jane Carlton, PhD, a
parasitologist from NYU Langone Medical Center, unraveled the genetic structure
of the malaria-causing parasite, one of four species of malarial parasite that frequently
infect humans. They identified only 150 genes specific to Plasmodium vivax,
according to the Oct. 9 issue of the journal Nature.
The authors of the study mentioned that the importance of
research into this form of malaria has been taken too lightly, despite the fact
that Plasmodium vivax leads to an estimated 300 million cases of the infectious
disease in populous countries like India
and Papua New Guinea.
Malaria parasites are transmitted by female Anopheles
mosquitoes. The multiplication of parasites within red blood cells causes
symptoms of anemia, nausea, fever, flu-like illness, and in severe cases, leads
to coma and death. Contracting the disease can be prevented by using mosquito
nets and insect repellent, as well as through mosquito control measures such as
spraying insecticides inside houses and draining eliminating water where
mosquitoes reproduce.
Mapping the genomes of P. vivax "it's going to be a
very powerful tool," said lead researcher Carlton.
Vivax malaria is so devastating that those who become
infected with the parasite, most of whom are deprived, are not able to support
themselves or their family members. "Vivax is one of the stealth reasons
that poor people can't escape poverty," according to Peter Hotez,
president of the Sabin Vaccine Institute at George Washington University and an
expert in tropical diseases.
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