Arthritis’ drugs glucosamine and chondroitin sulfate might
no longer be prescribed as they proved inefficient in slowing the disease
according to a study in the journal Arthritis & Rheumatism.
The study involved 572 arthritis patients who were followed
for 18 months. They were given either glucosamine and chondroitin or placebos.
At the end of the follow-up period, the researchers found that arthritis
actually worsened in 24 percent of participants taking the supplements, similar
to those taking placebo. More exactly, the supplements did not appear to slow
the loss of cartilage.
“We
don’t have good evidence that it (glucosamine and chondroitin sulfate
combination) slows (disease) progression,” rheumatologist Allen Sawitzke,
professor of internal medicine at the University of Utah
and author of the study, said.
However, he added that more studies need to be done before
labeling these supplements with a “not-working” label because they might prove
valuable in future studies.
The study was an extension of the National Institutes of
Health-funded Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) in
which researchers followed close 1,600 patients who took one or both of the
supplements, the painkiller Celebrex or placebo for six months. The study found
no significant change in arthritis patients taking the supplements. Those
patients suffered the same pain as patients given Celebrex or placebo.
Whether or not supplements sales would suffer loss following
this study’s findings remains to be seen. According to the Nutrition Business
Journal, the combination glucosamine chondroitin is the sixth-top-selling
dietary supplement in the US
with annual sales of $831 million in 2007.
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