An estimated 7,000 children end up in hospital emergency
rooms year because of cough and cold medicines, according to a study released
Monday by the U.S. Centers for Disease Control and Prevention.
“In the majority of cases, there ER visits are due to
unsupervised ingestion,” said lead author of the study Dr. Melissa K. Scaefer,
of the CDC’s Division of Healthcare Quality Promotion.
There were also cases (about one quarter) in which parents
gave children the proper dosage but they suffered an allergic reaction or some
other problem developed, the study reported.
The study included both over-the counter and prescription
medicines. The study comes less than two weeks after the U.S. Food and Drug
Administration warned parents not to give children under age 2 over-the counter
cough and cold medicines “because serious and potentially life-threatening side
effect can occur.”
The researchers cited a national survey that showed 64
percent of parents consider cough and cold medications to be safe and 20
percent plan to continue to give them to their children under 2 years, despite
the FDA’s warning.
“However, if these medications are removed from the market,
caregivers may be tempted to substitute products that are labeled for use by
older children and adults,” the CDC team wrote.
The study gathered data emerged from the National Electronic
Injury Surveillance System-Cooperative Adverse Drug Event Surveillance system, from
January 1, 2004 through December 31, 2005, which includes 63 emergency
departments around the country.
“Annually, an estimated 7,091 patients aged under 12 years
were treated in emergency departments for adverse drug events from cough and
cold medications, accounting for 5.7 percent of emergency department visits for
all medications in this age group,” the researchers wrote.
The researchers were unable to determine what symptoms the
children experienced in most of the cases. However, in those cases where that
information was available, 19 percent had allergic reactions and 13 percent had
neurological symptoms such as sleepiness or problems walking.
Children ages 2 to 5 accounted for 64 percent of the cases
and nearly 80 percent of the cases in this age group involved situations where
children took the medicines without their parents’ knowledge.
Ninety-three percent of the cases did not need
hospitalization, but about 7 percent required additional treatment.
Based on the findings, the researchers recommended the companies
that produce such medicines to change the packaging to keep small children from
getting the medications, which are often flavored and colored to make them more
appealing, Schaefer’s team said.
"One packaging innovation is incorporating adaptors onto bottles of
liquid medication such that medication can only be accessed with a needle-less
syringe, which prevents unsupervised preschool-aged children from drinking
directly from the bottle," they suggested.
"We had also considered the idea of taking coloring out of these
medications," Schaefer said in a telephone interview with Reuters.
However, the most important recommendation the researchers made was that
parents should not leave such medication in the hands of a 3-year-old and they
also should carefully supervise their children.
The study, supported by the CDC and the Department of Energy
was published online Monday. It will appear in the April issue of Pediatrics, a
journal of the American
Academy of Pediatrics.