British researchers revealed Thursday that birth control
pill could protect women against ovarian cancer for 30 years or longer after
they stop taking them.
Birth control pills have prevented 100,000 ovarian cancer
deaths worldwide so far, and 200,000 women from developing cancer of the ovary,
the researchers led by Valerie Beral, head of the Cancer Research UK
epidemiology unit at University of Oxford wrote in the journal Lancet.
The new study is the first to discover the benefits of the
pill when it comes to ovarian cancer.
“When you are 60 it matters whether you took it for five
years or 10 years in your twenties. The longer you took it, the better off you
are when the risk of ovarian cancer is high,” Beral said in a telephone
interview with Reuters.
The findings result from the analysis of 45 studies on
ovarian cancer in 21 countries and show that the benefits of the contraceptive
pill outweigh the risks.
“The eventual reduction in ovarian cancer is bigger than any
increase in other types of cancer caused by the pill,” the researcher said.
The study shows that 10 years of taking the pill reduced the
incidence of ovarian cancer before age 75 from 12 cases per 1,000 women to
eight. Those who take it for 15 years cut their risk by half. Death were cut
from seven women per 1,000 to five.
What is the most significant finding of the research is that
protection lasted for more than 30 years after pill use was stopped. This is important,
as ovarian cancer is commoner in older women who have passed the menopause.
“More than 100 million women are now taking the pill, so the
number of ovarian cancers prevented will rise over the next few decades to
about 30,000 per year,” the study said.
Over the time, the contraceptive pills were thought to be
harmful because they increase the risk of blood clots. However, a study of the
pill dated on last September, spanning 36 years and run by the Royal College of
General Practitioners, showed that it reduced the risk of three cancers - ovarian,
womb and bowel in women who took it for up to eight years.
“Young women don’t have to worry about cancer from taking
the pill because the eventual reduction in ovarian cancer is bigger than any
increase in other types of cancer caused by the pill,” Sir Richard Peto,
professor of epidemiology at Oxford
University said.
Two Canadian researchers explained in a commentary for the
Lancet that the protection offered by the contraceptive pills “stems from the
cumulative suppression of ovulatory cycles.” Therefore, oral contraceptives
“could help to decrease the number of cells that are likely to become malignant
over a lifetime, whereas HRT after menopause could have a carcinogenic effect,”
Eduardo Franco and Eliane Duarte-Franco from McGill University
and the Institut National de Sante Publique du Quebec said.
Following this research, experts called for better access to
oral contraceptives, arguing that the drugs should now be available over the
counter.
According to the International Agency for Research on
Cancer, there are more than 190,000 new cases of ovarian cancer a year
worldwide.