Adults with type 1 diabetes who use
continuous glucose monitoring devices to control their blood sugar more
effectively compared to the old-fashioned method of pricking their fingers
throughout the day can gain better control over their disease, according to a
new study.
Continuous glucose monitoring systems, or
GGM, measure blood glucose level readings every few minutes and using the data
obtained, patients can adjust their insulin injections as needed. A small
sensor sounds an alarm if blood sugar rises or falls to dangerous levels.
The old-fashioned-method of blood sugar
monitoring involves pricking a finger for blood and testing glucose levels
using a separate device.
The study, published online Monday by the New
England Journal of Medicine, included 322 adults and children – between the
ages of 8 to 72, with Type I diabetes. The initial results of the multicenter
clinical trial paid for by the Juvenile Diabetes Research Foundation were
presented Monday during the European Association for the Study of Diabetes’
annual meeting in Rome.
Some patients were assigned to a control
group using standard blood sugar monitoring, which involves manually pricking a
finger for blood and testing glucose levels using a separate meter. Others were
assigned to a control group using a continuous glucose monitoring device which
is attached to the body using a tiny catheter that measures blood glucose
levels and produces readings every few minutes.
Researchers monitored the patients’ A1c
levels (glycated haemoglobin or HbA1c), an average of a patient’s blood sugar
levels over the past several months. Patients were put into one of three age
groups - 8 to 14 years, 15 to 24 years and 25 years or older. An A1c goal for
an adult with diabetes is below 7%, and the aim for children is below 7.5%-8%,
the researchers found.
The adults aged 25 and older had the most
significantly improved control of blood sugar, the researchers found. Their A1c
levels decreased during the study period of 26 weeks by an average of 0.53%
compared with control patients. The study showed little effect of continuous
glucose monitoring in patients aged 8 to 15 compared to patients using the
traditional method of pricking a finger. In the other age groups, patients
using continuous glucose monitoring fared no better than patients using the
traditional method.
“One important practical implication is
that this is the first study to definitively provide good evidence of the
benefit of continuous glucose monitoring — the type of evidence needed for insurers
to agree to pay for it,” says study author Roy Beck, executive director of the
Jaeb Center for Health Research in Tampa.
Doctors and manufacturers are trying to
persuade more insurance companies to pay for the devices, which cost about $500
to $1,000. The study was funded by the Juvenile Diabetes Research Foundation, a
New York-based nonprofit research group.
Diabetes is the fifth leading cause of
death in the United States.
There are some 21 million Americans living with this disease, with 6.2 million
not even knowing that they have it. An estimated 8 percent of people in the U.S. have
type-2 diabetes, which can be associated with obesity and lack of exercise. Diabetes
risk factors include being overweight, sedentary, a family history of diabetes.