All the 48 passengers aboard a commuter plane died after the aircraft crashed into a suburban Buffalo home on Thursday. A bystander was also killed in the fiery crash.

The crash of Continental Connection Flight 3407 occurred at about 10:20 p.m. The Q400 Bombardier aircraft, operated by Colgan Air, was on its way from Newark Liberty International Airport in New Jersey to Buffalo Niagara International Airport.

According to eyewitnesses, who are used with planes flying above their city, the 74-seat plane did not sound right. It sounded louder than usual and made some strange noises.

"It [the plane] was not spiraling at all. The left wing was a little low," Tony Tatro told WGRZ-TV.

Bob Dworak, who lives near the house into which the plane crashed, said he saw the plane going down and then the huge flames that erupted into the sky.

"The whole sky was lit up orange," he said.

The number of deaths was confirmed by state police spokeswoman Rebecca Gibbons. The cause of the crash it’s unknown, but the plane was flying in conditions of light snow, fog and 17 mph winds.

An investigation is in preparations and will soon be launched by the National Transportation Safety Board. The operator of the plane, Colgan Air, a subsidiary of Pinnacle Airlines, operates planes under the Continental Connection, United Express and US Airways Express names.

This is the first deadly crash of a commercial airliner in America since Aug, 2006, when the same number of people (49) died after a Comair plane took off from a Lexington, Ky., and crashed because the runway was too short.