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Women who are proven to have a high risk of developing
breast cancer usually choose the double mastectomies as a protective measure
against cancer's rebound, doctors said Tuesday. That’s exactly what actress
Christina Applegate, 36, did in her case.
The preventive
mastectomy is commonly called a prophylactic mastectomy.
During her first
public appearance after her battle with cancer, the star told US breakfast
Show Good Morning America, she was "100% clear and
clean" following the procedure. She also explained she carries the BRCA 1
gene mutation. Over a lifetime, BRCA 1 can increase the risk of the disease by
as much as 85 percent. She said her choice of a prophylactic mastectomy was to
pre-empt the possibility of developing breast cancer in the future. Nancy
Priddy, Applegate’s mother, also survived breast cancer and helped support the
film and TV star in fighting with the disease.
Applegate says she opted for a double mastectomy after
learning of the genetic mutation. Only about 5% to 7% of breast cancers carry
these mutations, says Mehra Golshan, director of breast surgical services at Boston's Dana-Farber
Cancer Institute.
The International Journal of Cancer presented some research studies according to
which 18% of women with the mutations took this step. More than 50% of
the women had their ovaries removed, which reduces the risk of both breast and
ovarian cancers by removing the body's major source of estrogen.
During reconstructive surgery, doctors reconstruct a breast
by taking skin from the stomach, buttock or back, and reconstruct the chest
area over a saline implant.
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