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Japanese and American scientists discovered a way to make stem
cells out of human skin cells, an announcement that could mean the end of the opposition
regarding stem cell research.
Until now, human stem cells were taken from a human embryo a
few days after its fertilization. During the process the embryo was destroyed.
Both announcements were made on November 20 by the American
and Japanese scientist, the Current online reports.
James Thomson, University of Wisconsin-Madison scientist, published
a study in the journal Science. According to it, he could produce human embryonic
stem cells from a skin cell. He didn’t use or destroy any embryos in the
process.
Shinya Yamanaka, of Kyoto
University in Japan,
announced the same discovery which he published in the journal Cell.
A similar discovery was made last year and it was also
thought that it could trigger the end of the political and religious
opposition. Once the human eggs were eliminated from the process, scientists thought
that the religious opposition will drop. But it wasn’t the case.
Some religious groups might reject the stem cell research on
grounds that scientists may be “playing God.”
In his research Thomson used a retrovirus to produce four
genes into human skin cells from fetuses and foreskins from circumcisions. The cells
that were treated turned back to an embryonic state. Now his lab is growing
reprogrammed cells that are produced from adult cells from breast and abdominal
skin.
Yamanka used in his research skin cells from an adult’s
cheek. He said that his cells appear very similar to the embryonic stem cells,
but it is too early to say if the embryonic cells could be replaced by the
reprogrammed cells.
Yamanka carried his research on mice and identified in their
skin cells four genes that could turn other genes to make skin cells act like
embryonic stem cells, Voice of America informs.
According to researchers, it must be confirmed that the
reprogrammed human skin cells are similar with the stem cells from human
embryos. It will take some time until they could be tested on people.
Still, the breakthrough means that stem cells can be grown
using a cell from one individual.
There is however one concern and that is the cells might cause
cancer because the retroviruses that are used to reprogram the skin cells may
bring changes in their genes.
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