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Researchers from Indiana University School of Medicine say
biomarkers (chemicals in blood) in the blood can help identify mood disorder. This
discovery may help the medical community come up with better treatment for the
conditions.
These biomarkers”may offer an unexpectedly informative
window into brain functioning and disease state,” reported Alexander Niculescu III,
MD, PhD, assistant professor of psychiatry, medical neurobiology, and
neuroscience at Indiana
University’s medical
school who led the study.
Bipolar disorder and other conditions such as depression are
currently diagnosed based on the patient’s description of their symptoms and
the physician’s judgment. This makes it difficult to get an accurate diagnosis
or determine the severity of a patient’s condition.
Dr. Niculescu and his colleagues have shown that 10 genes
that can be detected in the blood could provide a better way to assess a patient.
“Patients aren’t sure how ill they really are, and neither
is the clinician – sometimes dismissing their symptoms, sometimes
overestimating them. Having an objective test for disease state, disease
severity, and especially to measure response to treatment, would be a big step
forward,” Dr. Niculescu wrote in the study published Tuesday in the Journal
Molecular Psychiatry.
However, Dr. Niculescu said more study is needed to confirm
these findings, adding that tests could be available in as little as five
years.
The study was supported by National Institutes of Health
grant funding, NAESAD and funds from Eli Lilly and Co.
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