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Scientists from the National Institute of Standards and
Technology and the University of Colorado at Boulder
discovered that if a person’s breath is tested with a laser light, it can
detect molecules related to diseases like asthma or cancer.
According Jun Ye, the leader of the research team from JILA,
a joint institute
of NIST and CU-Boulder, the
technique will offer a bigger picture for the molecules in just one breath.
When people breathe, a mixture of gases is inhaled like nitrogen,
oxygen, carbon dioxide, water vapor and traces of gases like carbon monoxide,
nitrous oxide and methane.
Exhaling, we eliminate less oxygen, more carbon dioxide and
over thousand of molecules, which are there in trace amounts.
So, excess methylamine may indicate liver problems and
kidney disease, while ammonia may show a sign of renal failure. Also Ye says
that high levels of acetone can point to diabetes and nitric oxide levels may show
signs of asthma.
According to Ye, information about a disease may be gathered
if breath molecules are identified simultaneously.
For example asthma may be detected when carbonyl sulfide,
carbon monoxide and hydrogen peroxide are traced altogether with nitric oxide.
Ye says that the equipment is not that selective in order to
choose a set of rare biomarkers or it cannot trace particular amounts of molecules
which are exhaled in the human breath.
Ye said: "The new technique has the potential to be
low-cost, rapid and reliable, and is sensitive enough to detect a much wider
array of biomarkers all at once for a diverse set of diseases," medicalnewstoday.com
reports.
The technique was tested on a group of volunteer students who
had to breathe into an optical cavity while sets of ultra fast lasers were transmitted
into it. They found that the technique permits for many gases to be analyzed at
the same time and to diagnose a disease.
The report can be found in the February edition of Optic
Express.
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