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Antibiotic drugs commonly used by patients suffering from
sinus infections, are not always effective, a recent study shows.
Sinus infection or sinusitis is one of the most common
complications of the common cold or flu. People suffering from sinusitis may
experience headaches, pressure in the eyes, cheeks and nose, nasal congestion
with thick nasal secretions, cough and fever.
British researchers at the University
of Southampton in Britain stated
that antibiotics used in treating this disease might not be very helpful.
Ian G. Williamson lead author of the study and his team analyzed
240 patients, aged 16 and older, who had sinus infection caused by bacteria. Participants
were divided in four groups, first being given amoxicillin, an antibiotic often
used for bacterial sinus infections and 400 units of steroid spray for 10 days.
Second group received only amoxicillin,
the third only steroid spray and the fourth placebo.
After 10 days, patients who did not receive any treatment
were as likely to be cured as those following a treatment with antibiotics.
“Our main conclusions are that among patients with the typical features of
acute bacterial sinusitis, neither an antibiotic nor a topical steroid alone or
in combination are effective in altering the symptom severity, the duration, or
the natural history of the condition. Topical steroids are likely to be
effective in those with such features but who have less severe symptoms at
presentation to the physician,” the authors of the study concluded.
Although antibiotics are designed to combat bacteria, they are
not always effective with bacterial infections because the drugs have
difficulty reaching the sinuses, said Vincenza Snow, director of clinical and
quality of care at the American
College of Physicians.
The findings should lead to a “reconsideration of antibiotic
use for acute sinusitis,” said Williamson.
He also recommended other methods, which have shown to be effective
in treating this disease such as inhaling steam and squirting salt water into
the nose to flush out thick mucous.
The findings were reported in the December issue of the
Journal of American Medical Association.
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