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Alcohol use and smoking have long been known to have noxious
influences on our health. New research comes to reinforce the idea saying that
heavy smokers and drinkers are for more likely to develop Alzheimer’s disease
earlier than people who do not smoke or drink.
The study, presented at the American
Academy of Neurology annual meeting by
a team of researchers from Mount Sinai
Medical Center
in Miami Beach,
analyzed 938 people aged 60 or older diagnosed with possible or probable
Alzheimer’s (a disease known to cause confusion, memory loss and behavioral
problems).
The researchers led by Ranjan Duara of the Mount Sinai Medical
Center in Miami Beach asked family members to provide
patients’ histories of drinking and smoking. The team further identified
patients who had APOE4, a gene that increases the risk of developing Alzheimer’s
late in life.
The study found patients who drank more than two alcoholic
drinks a day developed Alzheimer’s nearly five years earlier than people who
did not drink that much. Patients who smoked a pack a day or more developed the
disease 2.3 years sooner. Also, patients who had the APOE4 gene developed the
disease three years earlier than those who did not have it.
Overall, patients with the gene who smoked and drank too
much developed the disease nine years earlier (average 69) than patients without
those risk factors (average age 77).
“It's possible that if we can reduce or eliminate heavy smoking and
drinking, we could substantially delay the onset of Alzheimer's disease for
people and reduce the number of people who have Alzheimer's at any point in
time,” Dr. Duara said, according to BBC News.
“It has been projected that a delay in the onset of the disease by five
years would lead to a nearly 50 percent reduction in Alzheimer’s cases,” Dr.
Duara added.
This study on “bad habits” influencing the development of Alzheimer’s was
accompanied by a second one, presented at the same meeting in Chicago, which
stated that high cholesterol levels at 40 increased the risk of Alzheimer’s by
about 50 percent.
The study was conducted by Rachel Whitmer, a research scientist with the
Kaiser Permanente division of research in Oakland.
High cholesterol levels were defined as levels between 249 and 500 milligrams.
The findings of these two studies lead to a very simple conclusion. “The
best way to reduce risk is to eat a balanced diet rich in antioxidants and
vitamins and to exercise regularly. Not smoking, drinking only in moderation
and getting your blood pressure and cholesterol checked regularly throughout
life are also important ways people can reduce their risk of dementia,” Dr.
Susanne Sorenson, head of research at the Alzheimer’s Society said.
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