Adipose Tissue-derived Stem Cells in Breast Reconstruction

By Monica Comersan
01:07, December 18th 2007
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Adipose Tissue-derived Stem Cells in Breast Reconstruction

A recent Japan study on breast reconstruction with adipose-derived stem and regenerative cells proved to have successful results. The study was conducted on 21 women with partial mastectomy.

The breast tissue increased significantly within one month of reconstruction. The improvement was maintained more than 12 months of follow-up.

The study’s results were presented at the San Antonio Breast Cancer Symposium by Keizo Sugimachi, M.D., Ph.D., of Kyushu Central Hospital in Fukuoka.

The reconstruction procedure had had a significant satisfying impact on the study subjects as 79 percent of them declared that they are pleased with the outcome of the trial.

The Japan scientists have declared that they followed some patients as long as 18 months ant the tissue absorption was not significant and its thickness was satisfying. This positive outcome made them hopeful that this technique produces durable results.

The technique was developed by the Cytori Therapeutics of San Diego. The adipose tissue is extracted from the patient by standard liposuction procedures. Half of the extracted tissue is used as the primary filler tissue and the other half is processed to extract regenerative and stem cells. This processed half is combined with the first one and the mixture is injected into three 2–mm incisions in the patient’s breast as its reconstruction needs.

The technique proved so successful that Cytori declared that it will initiate two other clinical studies next year in Europe to further evaluate the procedure.



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