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One of the issues that stirred the interest
of researchers at the International AIDS Conference last week was the fact that
people living with genital herpes are at high risk of contracting HIV. Health
officials are worried about the situation because several studies suggested
that genital herpes could actually double a person’s risk for contracting HIV.
Studies
also suggested that long-term treatment of genital herpes with the drug
acyclovir does not reduce the rate of new HIV infections.
Reports show the herpes rate is higher
among women, black people and gay men.
Dr. C. Celum of the University of
Washington, Seattle, and colleagues evaluated the effects of the drug acyclovir
in a study that involved 1,814 gay men who have sex with men from the United
States and Peru, and in 1,358 women from Zimbabwe, Zambia and South Africa.
They were infected with HSV-2 but not with HIV.
One group was given placebo
pills and the second group took acyclovir. At the end of the study, researchers
found the incidence of genital ulcers was significantly lower in the acyclovir
group, but the incidence of HIV infection was the same in both the groups. These
results led them to the conclusion that the condition facilitates the spread of
virus and highlights the risk of contacting HIV, but it doesn’t represent a
risk factor for HIV.
Genital herpes is a sexually transmitted
disease (STD) caused by the herpes simplex viruses type 1 (HSV-1) and type 2
(HSV-2), according to the Centers for Disease Control and Prevention. Most
genital herpes is caused by HSV-2. Genital HSV-2 infection affects at least 45
million Americans ages 12 and older. It is more common in women. One out of
four women is diagnosed with a fist episode of genital herpes.
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