Genentech’s cancer drug Avastin is now facing a halt in
approval for expanded use because of its price tag, the U.S. Food and Drug
Administration said.
Avastin or bevacizumab is a therapeutic antibody designed to
inhibit the vascular endothelial growth factor (VEGF) protein. More exactly the
drug simply interferes with the blood supply to a tumor, thus cutting its
ability to grow and spread in the body.
The FDA approved the drug for use in patients with advanced
lung, colon, and breast cancer. The medication can cost up to $100,000 per year
and, although that expensive, the drug may only help people live longer by just
a few months.
According to Dr. Leonard Saltz, a colon cancer specialist at
The drug gives patients a sense of well-being and the
ability to carry out daily tasks without exhaustion or pain. The symptoms of
cancer are reduced only in cases when the disease is not that aggressive.
That’s why one cannot completely justify its cost, the FDA said, thus wondering
the approval for expanded use of the drug.
However, Avastin is being tested in as many as 450 clinical
trials for about 30 types of cancer, according to a report in the New York
Times. About 100,000 Americans take Avastin, according to its manufacturer.
“The quest is to eliminate the disease. And, yes, there is going to be a cost to that,” Arthur D. Levinson, Genentech's chief executive officer said, supporting the whopping cost of the drug.