Also Ms. Witherspoon will serve as the Honorary Chairman of the Avon Foundation, focusing on breast cancer, domestic violence and emergency relief initiatives, and she will be the spokeswoman for Avon's beauty brands and Sales Representatives.

"I am truly impressed by how Avon has been able to effect real change in the communities in which it does business and by how committed the company is to providing economic and personal fulfillment to women all over the world," said Witherspoon, who earned a Oscar award for Best Actress in 2005 for her portrayal of June Carter Cash in "Walk The Line."

She is also famous for her roles in movies like “Cruel Intentions”, “Legally Blonde” and “Sweet Home Alabama”

The exact terms of Witherspoon’s multiyear agreement with Avon weren’t disclosed.

"We are thrilled to welcome Reese as our global ambassador and believe she will give a strong voice to the company's commitment to empowering women," said Andrea Jung, chairwoman and chief executive officer of Avon Products Inc.

Last year Witherspoon divorced Ryan Philippe, to whom she married in 1999, after they co-starred in “Cruel Intentions”.